Leigh syndrome
Background
Leigh syndrome: Leigh's disease; Leigh's Encephalopathy
This is a progressive disease affecting the brain. The clinical course is very variable.
Most patients have problems by the age of two years, deteriorate rapidly and die within a year or two. Other patients have a step-wise downhill course starting later in childhood: these patients may deteriorate suddenly and then show partial recovery, followed by periods in which their condition is stable.