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Leigh syndrome

Background

Leigh syndrome: Leigh's disease; Leigh's Encephalopathy

This is a progressive disease affecting the brain. The clinical course is very variable.

Most patients have problems by the age of two years, deteriorate rapidly and die within a year or two. Other patients have a step-wise downhill course starting later in childhood: these patients may deteriorate suddenly and then show partial recovery, followed by periods in which their condition is stable.

What are the symptoms? View What are the symptoms?

Medical text written November 2000 by Dr A Morris. Last updated August 2005 by Dr A Morris, Consultant Paediatrician with Special Interest in Metabolic disease, Willink Biochemical Genetics Unit, Royal Manchester Children's Hospital, Manchester, UK.

 

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