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Huntington's disease

Background

Huntington's disease: Huntington's Chorea

Huntington's disease (HD) is a neurodegenerative disorder, characteristically affecting the basal ganglia but also affecting other areas of the central nervous system. Onset is usually in the fourth or fifth decade, but HD can occur more rarely in childhood or extreme old age.

Juvenile Huntington's disease
The age of onset of HD is very variable: in around five per cent of cases onset can be under the age of twenty years and in very rare cases the onset can be under the age of ten years. Given that juvenile HD (JHD) is defined by the age of onset, it follows that at any one time a number of people who started with HD under the age of twenty years will now be over twenty years old.

What are the symptoms? View What are the symptoms?

Medical text written November 1996 by Dr S Simpson. Last updated September 2005 by Dr S Simpson, Associate Specialist/ Senior Lecturer in Clinical Genetics Clinical Genetics, Grampian University Hospitals, Aberdeen, UK. Additional material on Juvenile Huntington's disease written July 2005 by Dr D O Quarrell, Consultant in Clinical Genetics, Centre for Human Genetics, Sheffield, UK.

 

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